A Greek Validation Study of the Multiple Sclerosis Work Difficulties Questionnaire-23

The Multiple Sclerosis Work Difficulties Questionnaire-23 (MSWDQ-23) is a self-report instrument developed to assess barriers faced by People with (PwMS) in the workplace. aim of this study was explore psychometric properties Greek version MSWDQ-23. sample consisted 196 PwMS, all currently working part- or full-time jobs. Participants underwent clinical examination and cognitive screening Brief International Cognitive Assessment for (BICAMS) completed measures fatigue, psychological functioning, quality life, along MSWDQ-23 questionnaire. Confirmatory Factor Analysis (CFA) performed, goodness-of-fit were used evaluate construct validity. Convergent validity checked correlating scores measures. Cronbach’s alpha value produced internal consistency. CFA yielded model fair fit confirming three-factor structure instrument. Higher work difficulties associated higher Expanded Disability Status Scale (EDSS) scores, poorer function, more stress, anxiety, depression, health status, supporting convergent Internal consistency (Cronbach’s = 0.94) test–retest reliability (ICC 0.996, 95%, CI 0.990–0.998) excellent. can be considered valid patient-reported outcome measure interventions aiming improve vocational status PwMS.